Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3ND07_GASACThioredoxin domain-containing protein. (432 aa)    
Predicted Functional Partners:
G3PE57_GASAC
Thioredoxin-related transmembrane protein 1.
   
 
 0.759
G3NTN2_GASAC
RIC3 domain-containing protein.
    
 0.724
G3Q847_GASAC
Endoplasmic reticulum oxidoreductase beta.
   
 0.680
G3PXH5_GASAC
Calnexin.
   
 0.668
G3Q3I1_GASAC
Calmegin.
   
 0.667
G3PM80_GASAC
Cytochrome b5 reductase 4.
  
 0.641
G3PPP5_GASAC
Unc-50 homolog (C. elegans).
      
 0.634
SCCPDH
Saccharopine dehydrogenase a, tandem duplicate 1.
     
 0.619
G3QA90_GASAC
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.612
G3NA48_GASAC
Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase).
   
 
 0.611
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (62%) [HD]