Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGO3Argonaute RISC catalytic component 3; Belongs to the argonaute family. (835 aa)    
Predicted Functional Partners:
G3Q9N5_GASAC
Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.
   
 0.942
G3NKF3_GASAC
Protein kinase, interferon-inducible double stranded RNA dependent activator.
    
 0.934
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.934
G3NWX4_GASAC
Si:dkey-217f16.6.
    
 0.897
G3Q6T9_GASAC
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.864
G3PFB6_GASAC
Trinucleotide repeat containing adaptor 6C1.
    
 0.852
G3PMS9_GASAC
Trinucleotide repeat containing adaptor 6A.
    
 0.852
G3Q6Y5_GASAC
Trinucleotide repeat containing adaptor 6C2.
    
 0.852
G3P815_GASAC
Family with sequence similarity 172 member A.
   
 
 0.792
G3N8X4_GASAC
Staufen double-stranded RNA binding protein 1.
   
 0.787
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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