STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3ND28_GASACComplement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family. (220 aa)    
Predicted Functional Partners:
C8A
Complement C8 alpha chain.
  
 0.996
G3PPM4_GASAC
NTR domain-containing protein.
   
 0.993
G3Q1B8_GASAC
Complement component 6.
   
 0.988
G3PTJ2_GASAC
Complement component 9.
   
 0.978
G3NR28_GASAC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
   0.923
G3PVB6_GASAC
Complement component 8, beta polypeptide.
   
 0.854
G3P9Q5_GASAC
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.850
G3Q4H0_GASAC
Uncharacterized protein.
   
 0.845
G3Q4X5_GASAC
Uncharacterized protein.
   
 0.845
G3Q4W5_GASAC
Uncharacterized protein.
   
 0.825
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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