Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TRHR1bThyrotropin-releasing hormone receptor 1b; Belongs to the G-protein coupled receptor 1 family. (399 aa)    
Predicted Functional Partners:
TRH
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
    
 0.996
G3NYP0_GASAC
Uncharacterized protein.
    
 0.827
G3NYS2_GASAC
Guanine nucleotide binding protein (G protein), alpha 14a.
    
  0.826
G3P5X7_GASAC
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
  0.826
G3PC64_GASAC
Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).
    
  0.826
GNB4
G protein subunit beta 4.
    
  0.824
G3PER0_GASAC
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.824
G3QAP3_GASAC
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.824
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
  0.813
G3NRG2_GASAC
Guanine nucleotide binding protein (G protein), beta 5a.
    
 0.793
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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