STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NDN2_GASACBRCA2 and CDKN1A interacting protein. (254 aa)    
Predicted Functional Partners:
G3N5P1_GASAC
Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family.
    
 
 0.929
G3NTL5_GASAC
Ribosome production factor 2 homolog.
   
  
 0.881
G3N7S4_GASAC
Cyclin-dependent kinase inhibitor 1A.
    
 
 0.866
G3PVZ2_GASAC
Brix domain containing 2.
   
    0.866
G3N9N6_GASAC
Nucleolar protein interacting with the FHA domain of MKI67.
   
    0.851
G3NUK0_GASAC
EBNA1 binding protein 2.
   
    0.847
G3NA42_GASAC
Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
   
    0.833
WDR12
Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
   0.830
G3NNK8_GASAC
IMP U3 small nucleolar ribonucleoprotein 4.
   
    0.821
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
    
 
 0.811
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.