STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (595 aa)    
Predicted Functional Partners:
TSHB
Thyroid stimulating hormone subunit beta.
    
 0.889
G3NNS4_GASAC
Thyroid stimulating hormone subunit beta a.
    
 0.881
LOC100174897
Luteinizing hormone, beta polypeptide.
   
 0.874
POMC
Proopiomelanocortin a.
   
 
 0.767
G3NP88_GASAC
R-spondin 2.
    
 0.761
G3NRS7_GASAC
R-spondin 3.
    
 0.761
G3PKF9_GASAC
R-spondin 1.
    
 0.755
G3N8Q1_GASAC
Vasoactive intestinal peptide.
     
 0.751
G3N861_GASAC
Uncharacterized protein.
    
 0.747
G3NS69_GASAC
Uncharacterized protein.
    
 0.747
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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