Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NE38_GASACUncharacterized protein. (933 aa)    
Predicted Functional Partners:
G3NPM0_GASAC
Cullin 1b; Belongs to the cullin family.
   
 0.975
G3QCJ8_GASAC
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.962
G3NXT5_GASAC
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.951
G3NY10_GASAC
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
 0.822
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.822
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.784
G3P6F7_GASAC
Denticleless E3 ubiquitin protein ligase homolog (Drosophila).
    
 
 0.755
G3Q4G0_GASAC
COMM domain containing 5.
     
 0.728
G3NPI0_GASAC
F-box and leucine-rich repeat protein 2.
   
 
 0.717
G3PMC3_GASAC
NEDD8 ubiquitin like modifier, like.
    
 0.707
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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