STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NE68_GASACDNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (910 aa)    
Predicted Functional Partners:
G3NP96_GASAC
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
  
0.999
G3NR70_GASAC
MutS homolog 3 (E. coli).
  
0.999
G3NHI8_GASAC
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
 
 0.997
G3P4K3_GASAC
PMS1 homolog 2, mismatch repair system component.
 
 0.997
G3NBZ1_GASAC
Exonuclease 1.
  
 0.993
G3NDQ4_GASAC
PMS1 homolog 1, mismatch repair system component.
 
 0.993
G3NQJ7_GASAC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.990
G3NXP2_GASAC
MutL homolog 3 (E. coli).
  
 0.975
G3PHK7_GASAC
DNA polymerase.
  
 
 0.952
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.946
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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