STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NE71_GASACGTP cyclohydrolase 2. (244 aa)    
Predicted Functional Partners:
G3NS53_GASAC
GTP cyclohydrolase I feedback regulator.
    
 0.976
ITPA
Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
  
 
 0.952
G3P7E1_GASAC
6-pyruvoyl tetrahydrobiopterin synthase.
  
 
 0.934
G3PM45_GASAC
Nudix (nucleoside diphosphate linked moiety X)-type motif 15; Belongs to the Nudix hydrolase family.
  
 
 0.922
G3PJY8_GASAC
Vesicle (multivesicular body) trafficking 1.
   
   0.916
G3NXP5_GASAC
NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae).
  
 
 0.901
G3NRQ7_GASAC
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.892
G3PC67_GASAC
Uncharacterized protein.
  
 
  0.885
G3PC70_GASAC
Uncharacterized protein.
  
 
  0.883
G3PC74_GASAC
Uncharacterized protein.
  
 
  0.883
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.