Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NEF1_GASACNuclear receptor coactivator. (1418 aa)    
Predicted Functional Partners:
G3PYI0_GASAC
Nuclear receptor subfamily 1, group H, member 3.
    
 0.916
G3NPT1_GASAC
Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
    
 0.902
G3NM42_GASAC
E1A binding protein p300 a.
   
 0.879
G3NY16_GASAC
E1A binding protein p300 b.
   
 0.879
G3PI74_GASAC
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
    
 0.872
G3NMG0_GASAC
Nuclear receptor subfamily 1, group H, member 5.
    
 0.862
G3PBM0_GASAC
CREB binding protein b.
   
 0.862
G3PD77_GASAC
Nuclear receptor subfamily 1, group H, member 4.
    
 0.862
G3Q4J0_GASAC
CREB binding protein a.
   
 0.862
PPARG
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
    
 0.829
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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