Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NEI1_GASACRenin; Belongs to the peptidase A1 family. (401 aa)    
Predicted Functional Partners:
G3P5J3_GASAC
Angiotensinogen; Belongs to the serpin family.
    
 0.885
G3NA66_GASAC
ATPase H+ transporting accessory protein 2.
   
 0.807
G3NZ72_GASAC
Cathepsin C; Belongs to the peptidase C1 family.
   
 0.760
G3P7I4_GASAC
Cathepsin Bb; Belongs to the peptidase C1 family.
   
 0.725
G3PUU3_GASAC
Cathepsin Ba; Belongs to the peptidase C1 family.
   
 0.725
G3N5R7_GASAC
Cathepsin Z; Belongs to the peptidase C1 family.
   
 0.714
G3PWF2_GASAC
Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.
   
 0.714
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
 0.711
G3NAF5_GASAC
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.688
G3NIE8_GASAC
Uncharacterized protein; Belongs to the peptidase C1 family.
   
 0.677
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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