Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NEM0_GASACDUF3504 domain-containing protein. (721 aa)    
Predicted Functional Partners:
G3P5C3_GASAC
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
   
 0.884
UBQLN4
Ubiquilin 4.
    
 0.833
G3PIR4_GASAC
Uncharacterized protein.
    
 0.688
G3NVJ3_GASAC
Chromobox homolog 3a (HP1 gamma homolog, Drosophila).
   
 
 0.621
CBX1
Chromobox homolog 1b (HP1 beta homolog Drosophila).
   
 
 0.586
G3NIY0_GASAC
AT rich interactive domain 4A (RBP1-like).
   
 0.586
G3NK22_GASAC
Translocase of outer mitochondrial membrane 20.
   
 0.586
CBX1-2
Uncharacterized protein.
   
 
 0.586
G3P4B2_GASAC
Chromobox homolog 5 (HP1 alpha homolog, Drosophila).
   
 
 0.583
G3N9I3_GASAC
Myb-like, SWIRM and MPN domains 1.
   
  0.573
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (52%) [HD]