Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NEV5_GASACSi:dkey-4e7.3. (319 aa)    
Predicted Functional Partners:
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
  
 
 0.769
G3P9D3_GASAC
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
  
 
 0.768
G3NY51_GASAC
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 0.766
G3Q6E3_GASAC
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
  
 0.766
G3NCU7_GASAC
Adenine phosphoribosyltransferase.
    
 0.765
AMDHD1
Amidohydrolase domain containing 1.
  
 
 0.740
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 0.686
G3Q2K2_GASAC
Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae).
   
 
  0.680
G3N661_GASAC
Single-strand-selective monofunctional uracil-DNA glycosylase 1.
   
 0.673
G3PE33_GASAC
CMP/dCMP-type deaminase domain-containing protein.
   
 0.673
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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