RNF5 protein (Gasterosteus aculeatus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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protein homology

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Score

RNF5

Ring finger protein 5. (195 aa)

Predicted Functional Partners:

G3NQ33_GASAC

0.855

G3P2X0_GASAC

0.844

G3PXT7_GASAC

0.844

G3NUA6_GASAC

0.820

G3PIX9_GASAC

0.820

G3PI80_GASAC

0.791

G3PPG4_GASAC

0.790

G3Q366_GASAC

0.790

G3NZ68_GASAC

0.786

G3QA52_GASAC

0.776

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3NQ33_GASAC	G3NUA6_GASAC	ENSGACP00000007449	ENSGACP00000008924	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	ER lipid raft associated 1.	0.748
G3NQ33_GASAC	G3P2X0_GASAC	ENSGACP00000007449	ENSGACP00000011943	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.860
G3NQ33_GASAC	G3PI80_GASAC	ENSGACP00000007449	ENSGACP00000017307	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.988
G3NQ33_GASAC	G3PIX9_GASAC	ENSGACP00000007449	ENSGACP00000017558	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Cholesterol 25-hydroxylase like 3.	0.749
G3NQ33_GASAC	G3PPG4_GASAC	ENSGACP00000007449	ENSGACP00000019498	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.980
G3NQ33_GASAC	G3PXT7_GASAC	ENSGACP00000007449	ENSGACP00000022426	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 185.	0.855
G3NQ33_GASAC	G3Q366_GASAC	ENSGACP00000007449	ENSGACP00000024316	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.980
G3NQ33_GASAC	G3QA52_GASAC	ENSGACP00000007449	ENSGACP00000026768	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin B.	0.702
G3NQ33_GASAC	RNF5	ENSGACP00000007449	ENSGACP00000003892	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ring finger protein 5.	0.855
G3NUA6_GASAC	G3NQ33_GASAC	ENSGACP00000008924	ENSGACP00000007449	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.748
G3NUA6_GASAC	G3NZ68_GASAC	ENSGACP00000008924	ENSGACP00000010640	ER lipid raft associated 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.654
G3NUA6_GASAC	G3PI80_GASAC	ENSGACP00000008924	ENSGACP00000017307	ER lipid raft associated 1.	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.	0.724
G3NUA6_GASAC	G3PIX9_GASAC	ENSGACP00000008924	ENSGACP00000017558	ER lipid raft associated 1.	Cholesterol 25-hydroxylase like 3.	0.674
G3NUA6_GASAC	G3PPG4_GASAC	ENSGACP00000008924	ENSGACP00000019498	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.703
G3NUA6_GASAC	G3PXT7_GASAC	ENSGACP00000008924	ENSGACP00000022426	ER lipid raft associated 1.	Ring finger protein 185.	0.820
G3NUA6_GASAC	G3Q366_GASAC	ENSGACP00000008924	ENSGACP00000024316	ER lipid raft associated 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.703
G3NUA6_GASAC	G3QA52_GASAC	ENSGACP00000008924	ENSGACP00000026768	ER lipid raft associated 1.	Ubiquitin B.	0.734
G3NUA6_GASAC	RNF5	ENSGACP00000008924	ENSGACP00000003892	ER lipid raft associated 1.	Ring finger protein 5.	0.820
G3NZ68_GASAC	G3NUA6_GASAC	ENSGACP00000010640	ENSGACP00000008924	Ubiquitin A-52 residue ribosomal protein fusion product 1.	ER lipid raft associated 1.	0.654
G3NZ68_GASAC	G3P2X0_GASAC	ENSGACP00000010640	ENSGACP00000011943	Ubiquitin A-52 residue ribosomal protein fusion product 1.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.	0.589