Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (267 aa)    
Predicted Functional Partners:
G3NDF1_GASAC
Thyrotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
TRHR1b
Thyrotropin-releasing hormone receptor 1b; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
TRHR1a
Thyrotropin-releasing hormone receptor 1a; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
TRHR3
Thyrotropin-releasing hormone receptor 3; Belongs to the G-protein coupled receptor 1 family.
    
 0.996
OXT
Oxytocin; Belongs to the vasopressin/oxytocin family.
   
 
 0.826
G3P1D7_GASAC
Phosphoinositide phospholipase C.
     
 0.820
NTS
Neurotensin.
     
 0.818
G3NEY4_GASAC
Corticotropin releasing hormone b.
      
 0.810
POMC
Proopiomelanocortin a.
      
 0.807
MC4R
Melanocortin 4 receptor.
    
 0.793
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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