Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NFS6_GASACMitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (897 aa)    
Predicted Functional Partners:
G3Q6L0_GASAC
Mitogen-activated protein kinase kinase 7.
    
0.950
MAP3K13
Mitogen-activated protein kinase kinase kinase.
  
  
 
0.903
MAP3K12
Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway.
  
  
 
0.901
G3NAH1_GASAC
MYC binding protein 2.
    
 
 0.888
G3NUC0_GASAC
FRA10A associated CGG repeat 1.
    
   0.547
CDC25B
Cell division cycle 25B.
   
  
 0.539
G3PFM8_GASAC
Mitogen-activated protein kinase 8 interacting protein 2.
    
 
 0.481
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 
 0.481
G3NBM7_GASAC
F-box protein 45.
    
 
 0.469
G3N430_GASAC
Sorting nexin 19b.
      
 0.456
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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