STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NFS8_GASACJunctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (742 aa)    
Predicted Functional Partners:
G3NZF2_GASAC
Uncharacterized protein.
   
 0.733
G3P6J6_GASAC
RAB guanine nucleotide exchange factor (GEF) 1, like.
   
 0.733
G3QC77_GASAC
RAB guanine nucleotide exchange factor (GEF) 1.
   
 0.733
G3NGI4_GASAC
Ankyrin repeat and SOCS box containing 11.
   
 0.625
G3NIB0_GASAC
Uncharacterized protein.
   
 0.625
G3PVQ6_GASAC
Uncharacterized protein.
   
 0.625
G3PW10_GASAC
Ankyrin repeat and SOCS box containing 5a.
   
 0.625
G3Q6R2_GASAC
Ankyrin repeat and SOCS box containing 13a, tandem duplicate 2.
  
 0.608
G3NKE0_GASAC
Uncharacterized protein.
   
 0.595
G3Q812_GASAC
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
 0.554
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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