Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
G3NG09_GASACThimet oligopeptidase 1. (685 aa)    
Predicted Functional Partners:
NTS
Neurotensin.
     
 0.830
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
  
 0.692
RIMS2
Regulating synaptic membrane exocytosis 2.
    
   0.687
G3PKL3_GASAC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.683
G3Q8G8_GASAC
Lumican.
      
 0.682
G3NIA8_GASAC
5-hydroxytryptamine (serotonin) receptor 5A, genome duplicate b; Belongs to the G-protein coupled receptor 1 family.
      
 0.681
G3NCJ9_GASAC
Neural precursor cell expressed, developmentally down-regulated 9.
      
 0.680
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
      
 0.679
G3PDN0_GASAC
Ninein (GSK3B interacting protein).
      
 0.635
G3NFT3_GASAC
Spindle and centriole associated protein 1.
      
 0.605
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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