Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NG22_GASACFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (366 aa)    
Predicted Functional Partners:
G3NBF3_GASAC
Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.
   
 0.844
G3PT82_GASAC
Cytochrome b5 type B; Belongs to the cytochrome b5 family.
   
 0.844
G3P7W5_GASAC
Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family.
   
 
 0.838
G3P886_GASAC
Cholesterol 25-hydroxylase like 1, tandem duplicate 1; Belongs to the sterol desaturase family.
   
 
 0.838
G3PIW8_GASAC
Cholesterol 25-hydroxylase like 3; Belongs to the sterol desaturase family.
   
 
 0.838
G3PT58_GASAC
Cholesterol 25-hydroxylase like 2; Belongs to the sterol desaturase family.
   
 
 0.838
G3PXU3_GASAC
Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.
   
 
 0.838
G3N841_GASAC
Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.
   
 0.799
G3PH14_GASAC
Alkylglycerol monooxygenase; Belongs to the sterol desaturase family.
      
 0.798
G3PM80_GASAC
Cytochrome b5 reductase 4.
   
 0.796
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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