STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPGRRetinitis pigmentosa GTPase regulator. (1132 aa)    
Predicted Functional Partners:
G3PFA1_GASAC
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
   
 0.951
G3Q0S4_GASAC
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.951
G3Q8S4_GASAC
RPGR interacting protein 1.
    
 
 0.941
G3NBG4_GASAC
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 
 0.918
RANBP2
RAN binding protein 2.
    
 0.917
G3PHQ9_GASAC
RAN binding protein 1.
   
 0.852
G3NLZ6_GASAC
Ran GTPase activating protein 1b.
   
 
 0.761
G3NXS0_GASAC
RAN GTPase activating protein 1a.
   
 
 0.761
G3NEI8_GASAC
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.724
G3NG86_GASAC
Importin subunit alpha; Belongs to the importin alpha family.
   
 
 0.724
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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