Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
G3NGC0_GASACMinichromosome maintenance complex binding protein. (631 aa)    
Predicted Functional Partners:
G3NKN1_GASAC
DNA helicase; Belongs to the MCM family.
   
 
 0.996
G3NUG2_GASAC
DNA helicase; Belongs to the MCM family.
   
 
 0.996
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.996
G3Q1D6_GASAC
DNA helicase; Belongs to the MCM family.
   
 
 0.993
G3PFI7_GASAC
DNA helicase; Belongs to the MCM family.
   
 
 0.992
G3N424_GASAC
DNA helicase; Belongs to the MCM family.
   
 
 0.991
G3NQU4_GASAC
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 
 0.978
G3PDI3_GASAC
Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family.
   
 
 0.933
G3PTY4_GASAC
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 
 0.928
G3PMQ5_GASAC
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 
 0.907
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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