G3NGJ8_GASAC protein (Gasterosteus aculeatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

G3NGJ8_GASAC

Makorin, ring finger protein, 2. (415 aa)

Predicted Functional Partners:

G3PDN7_GASAC

0.760

G3NWL2_GASAC

0.706

G3PCG6_GASAC

0.696

G3P3R5_GASAC

0.674

G3NX84_GASAC

0.629

G3NZ68_GASAC

0.601

G3QA52_GASAC

0.600

G3P3R3_GASAC

0.588

G3P6I0_GASAC

0.588

G3QBH0_GASAC

0.588

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3NGJ8_GASAC	G3NWL2_GASAC	ENSGACP00000004454	ENSGACP00000009731	Makorin, ring finger protein, 2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.706
G3NGJ8_GASAC	G3NX84_GASAC	ENSGACP00000004454	ENSGACP00000009953	Makorin, ring finger protein, 2.	Thyroid hormone receptor interactor 12.	0.629
G3NGJ8_GASAC	G3NZ68_GASAC	ENSGACP00000004454	ENSGACP00000010640	Makorin, ring finger protein, 2.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.601
G3NGJ8_GASAC	G3P3R3_GASAC	ENSGACP00000004454	ENSGACP00000012236	Makorin, ring finger protein, 2.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.588
G3NGJ8_GASAC	G3P3R5_GASAC	ENSGACP00000004454	ENSGACP00000012238	Makorin, ring finger protein, 2.	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.	0.674
G3NGJ8_GASAC	G3P6I0_GASAC	ENSGACP00000004454	ENSGACP00000013203	Makorin, ring finger protein, 2.	C2 tensin-type domain-containing protein.	0.588
G3NGJ8_GASAC	G3PCG6_GASAC	ENSGACP00000004454	ENSGACP00000015290	Makorin, ring finger protein, 2.	Ribosomal protein S27a.	0.696
G3NGJ8_GASAC	G3PDN7_GASAC	ENSGACP00000004454	ENSGACP00000015711	Makorin, ring finger protein, 2.	Hydroxyacylglutathione hydrolase.	0.760
G3NGJ8_GASAC	G3QA52_GASAC	ENSGACP00000004454	ENSGACP00000026768	Makorin, ring finger protein, 2.	Ubiquitin B.	0.600
G3NGJ8_GASAC	G3QBH0_GASAC	ENSGACP00000004454	ENSGACP00000027236	Makorin, ring finger protein, 2.	Transmembrane phosphatase with tensin homology.	0.588
G3NWL2_GASAC	G3NGJ8_GASAC	ENSGACP00000009731	ENSGACP00000004454	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Makorin, ring finger protein, 2.	0.706
G3NWL2_GASAC	G3NX84_GASAC	ENSGACP00000009731	ENSGACP00000009953	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Thyroid hormone receptor interactor 12.	0.863
G3NWL2_GASAC	G3NZ68_GASAC	ENSGACP00000009731	ENSGACP00000010640	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.814
G3NWL2_GASAC	G3PCG6_GASAC	ENSGACP00000009731	ENSGACP00000015290	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ribosomal protein S27a.	0.782
G3NWL2_GASAC	G3QA52_GASAC	ENSGACP00000009731	ENSGACP00000026768	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Ubiquitin B.	0.762
G3NX84_GASAC	G3NGJ8_GASAC	ENSGACP00000009953	ENSGACP00000004454	Thyroid hormone receptor interactor 12.	Makorin, ring finger protein, 2.	0.629
G3NX84_GASAC	G3NWL2_GASAC	ENSGACP00000009953	ENSGACP00000009731	Thyroid hormone receptor interactor 12.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.863
G3NX84_GASAC	G3NZ68_GASAC	ENSGACP00000009953	ENSGACP00000010640	Thyroid hormone receptor interactor 12.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.992
G3NX84_GASAC	G3PCG6_GASAC	ENSGACP00000009953	ENSGACP00000015290	Thyroid hormone receptor interactor 12.	Ribosomal protein S27a.	0.994
G3NX84_GASAC	G3QA52_GASAC	ENSGACP00000009953	ENSGACP00000026768	Thyroid hormone receptor interactor 12.	Ubiquitin B.	0.969