STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NGK0_GASACUncharacterized protein. (235 aa)    
Predicted Functional Partners:
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.990
G3NQH4_GASAC
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
 
  
 0.979
G3P2E3_GASAC
Forkhead box O3b.
    
 0.963
G3PCS3_GASAC
Fork-head domain-containing protein.
    
 0.963
G3Q7H8_GASAC
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
    
 0.963
G3PT13_GASAC
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
 
  
 0.959
G3Q5K8_GASAC
Sirtuin 7.
   
 0.946
G3PDU0_GASAC
Forkhead box O1 a.
    
 0.942
G3PRG1_GASAC
Sirtuin 6.
   
 0.942
G3PY01_GASAC
Forkhead box O4.
    
 0.936
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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