Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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G3NGK1_GASACGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)    
Predicted Functional Partners:
G3NSK8_GASAC
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
  0.965
HCRTR2
Hypocretin (orexin) receptor 2.
   
 0.953
AVPR1A
Arginine vasopressin receptor 1Aa.
    
  0.949
GHRHR
Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.
   
  0.939
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
    
  0.932
LHCGR
Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
    
  0.932
G3NY14_GASAC
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.
   
 0.929
G3NPE2_GASAC
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
   
 0.928
GNB4
G protein subunit beta 4.
   
 0.928
G3PER0_GASAC
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
   
 0.928
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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