STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NGM2_GASACAmyloid beta (A4) precursor protein b. (749 aa)    
Predicted Functional Partners:
G3NNS1_GASAC
Sortilin-related receptor, L(DLR class) A repeats containing.
    
 0.959
G3PRT9_GASAC
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.935
NCSTN
Nicastrin.
    
 0.917
G3NJV4_GASAC
Tumor necrosis factor receptor superfamily, member 21.
   
 
 0.904
G3NEX0_GASAC
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.900
G3QCM4_GASAC
Amyloid beta (A4) precursor protein-binding, family B, member 3.
   
 0.893
G3Q044_GASAC
Pitrilysin metallopeptidase 1.
    
 
 0.887
G3PBQ4_GASAC
Amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65).
   
 0.869
G3PUV6_GASAC
Amyloid beta (A4) precursor protein-binding, family B, member 2b.
    
 0.869
G3Q1F3_GASAC
Uncharacterized protein.
    
 0.869
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.