Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
G3NGZ2_GASACInhibitor of growth protein. (270 aa)    
Predicted Functional Partners:
G3PE38_GASAC
SIN3-HDAC complex associated factor.
    
 
 0.983
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.967
G3PMJ2_GASAC
SDS3 homolog, SIN3A corepressor complex component.
    
 
 0.949
G3NN24_GASAC
BRMS1 like transcriptional repressor b.
    
 
 0.944
G3QCA7_GASAC
Sap30-like.
    
 
 0.933
G3Q893_GASAC
BRMS1 transcriptional repressor and anoikis regulator.
    
 
 0.932
G3NIY0_GASAC
AT rich interactive domain 4A (RBP1-like).
   
 0.918
G3NK22_GASAC
Translocase of outer mitochondrial membrane 20.
   
 0.918
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.910
RBBP4-2
RB binding protein 4, chromatin remodeling factor.
   
 0.910
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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