Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NH56_GASACBiogenesis of lysosomal organelles complex-1, subunit 4, cappuccino. (241 aa)    
Predicted Functional Partners:
G3PXA6_GASAC
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
   
 0.998
G3NQY9_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 1.
    
 0.997
G3NH11_GASAC
Dystrobrevin binding protein 1b.
   
 0.995
G3NCH0_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 5, muted.
    
 0.985
G3P091_GASAC
Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.
    
 0.977
G3N5W4_GASAC
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
    
 0.972
G3Q8N0_GASAC
WASH complex subunit 3.
    
   0.948
G3N871_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 2.
   
 0.941
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
     
 0.882
BRK1
BRICK1 subunit of SCAR/WAVE actin nucleating complex.
    
   0.826
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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