Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
G3NH62_GASACInsulin receptor substrate 2b. (1061 aa)    
Predicted Functional Partners:
G3NUY1_GASAC
Growth factor receptor-bound protein 2b.
    
 0.989
G3P8C9_GASAC
Tyrosine-protein kinase receptor.
   
 0.981
G3PXN2_GASAC
Tyrosine-protein kinase receptor.
   
 0.981
G3PII8_GASAC
Tyrosine-protein kinase receptor.
    
 0.978
G3PPC2_GASAC
Tyrosine-protein kinase receptor.
    
 0.978
G3NAF5_GASAC
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.975
G3NM95_GASAC
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.962
G3NEZ0_GASAC
Suppressor of cytokine signaling 3.
    
 0.943
socs3
Suppressor of cytokine signaling 3a.
    
 0.943
G3NJC9_GASAC
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.936
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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