Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NRDCNardilysin b (N-arginine dibasic convertase); Belongs to the peptidase M16 family. (1089 aa)    
Predicted Functional Partners:
G3NEX0_GASAC
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
   
 
 0.897
G3NAF5_GASAC
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.868
G3PCG6_GASAC
Ribosomal protein S27a.
    
  0.868
G3NZ68_GASAC
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.800
G3QA52_GASAC
Ubiquitin B.
    
  0.769
G3NWW1_GASAC
Phosphopantothenoylcysteine synthetase.
    
   0.729
G3PF32_GASAC
Trehalase.
   
  
 0.675
G3PLD1_GASAC
Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae).
   
 
 0.667
G3NK94_GASAC
G patch domain containing 11.
    
 
 0.651
G3NVD2_GASAC
Oxidoreductase NAD-binding domain containing 1.
      
 0.650
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.