Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NHI8_GASACMutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (746 aa)    
Predicted Functional Partners:
G3NE68_GASAC
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
G3NP96_GASAC
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 0.999
G3P4K3_GASAC
PMS1 homolog 2, mismatch repair system component.
  
0.999
G3NDQ4_GASAC
PMS1 homolog 1, mismatch repair system component.
  
0.998
G3NR70_GASAC
MutS homolog 3 (E. coli).
 
 0.998
G3NS19_GASAC
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.998
G3NBZ1_GASAC
Exonuclease 1.
  
 0.997
G3NXP2_GASAC
MutL homolog 3 (E. coli).
    
0.997
G3NQJ7_GASAC
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.994
G3P9V9_GASAC
BLM RecQ like helicase.
  
 0.994
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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