Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NHN0_GASACPhospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (231 aa)    
Predicted Functional Partners:
G3P5V7_GASAC
Uncharacterized protein.
    
 
 0.674
G3PU07_GASAC
SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
    
 
 0.674
G3NHM1_GASAC
Zic family member 4.
    
 
 0.613
G3NQE2_GASAC
Pumilio RNA-binding family member 1.
    
 
 0.592
G3P589_GASAC
Pumilio RNA-binding family member 2.
    
 
 0.592
G3QCP6_GASAC
Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
    
 
 0.533
G3N461_GASAC
CCHC-type zinc finger, nucleic acid binding protein a.
    
 
 0.518
LOC100174881
XK-related protein 8; Promotes phosphatidylserine exposure on apoptotic cell surface, possibly by mediating phospholipid scrambling. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (By similarity); Belongs to the XK family.
      
 0.471
G3P5A8_GASAC
Ubiquinol-cytochrome c reductase core protein 1.
    
 
 0.452
G3Q733_GASAC
Peptidase (mitochondrial processing) beta; Belongs to the peptidase M16 family.
    
 
 0.452
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: medium (44%) [HD]