STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NHR7_GASACSclerostin. (202 aa)    
Predicted Functional Partners:
G3N651_GASAC
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.973
G3Q1Y1_GASAC
Mitogen-activated protein kinase.
   
 0.899
G3PAK1_GASAC
Protein tyrosine phosphatase non-receptor type 5.
    
  0.859
G3N4X3_GASAC
Uncharacterized protein.
   
 0.776
G3NYD7_GASAC
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.776
G3PIB8_GASAC
Mitogen-activated protein kinase.
   
 0.776
G3PN66_GASAC
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
 0.776
G3PSZ1_GASAC
Protein tyrosine phosphatase receptor type R.
   
 0.776
G3NQF0_GASAC
Mitogen-activated protein kinase.
   
 0.758
G3NVN6_GASAC
Mitogen-activated protein kinase.
   
 0.758
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.