STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MC2RMelanocortin 2 receptor. (291 aa)    
Predicted Functional Partners:
POMC
Proopiomelanocortin a.
    
 0.992
POMCb
Proopiomelanocortin b.
    
 0.901
G3N8Q1_GASAC
Vasoactive intestinal peptide.
   
 
 0.879
ADCYAP1
Adenylate cyclase activating polypeptide 1a.
    
 0.876
G3PY76_GASAC
Adenylate cyclase activating polypeptide 1b.
    
 0.876
MC4R
Melanocortin 4 receptor.
  
 
0.865
G3NHU4_GASAC
Melanocortin 5b receptor.
     
0.859
G3NNS4_GASAC
Thyroid stimulating hormone subunit beta a.
   
 
  0.857
TSHB
Thyroid stimulating hormone subunit beta.
   
 
  0.857
MC1R
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
     
0.842
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.