Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NHY0_GASACNAD(P)H dehydrogenase, quinone 1. (250 aa)    
Predicted Functional Partners:
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 
 0.683
G3NKM2_GASAC
Nuclear factor, erythroid 2-like 2a.
    
 0.639
G3PHV7_GASAC
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
  0.579
G3P0C3_GASAC
NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family.
    
   0.564
IYD
Iodotyrosine deiodinase.
  
 
 0.555
G3NL95_GASAC
Antizyme inhibitor 1a; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
  0.497
G3NNE8_GASAC
Antizyme inhibitor 1b; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
  0.497
G3NZ38_GASAC
Riboflavin kinase.
     
 0.480
G3NNT8_GASAC
Uncharacterized protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
    
  0.478
G3PRJ1_GASAC
Transmembrane and coiled-coil domains 3.
  
 
 0.421
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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