Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| G3N487_GASAC | G3NI54_GASAC | ENSGACP00000000107 | ENSGACP00000005014 | Replication protein A3. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.972 |
| G3N487_GASAC | G3NKI9_GASAC | ENSGACP00000000107 | ENSGACP00000005852 | Replication protein A3. | Excision repair cross-complementation group 4. | 0.732 |
| G3N487_GASAC | G3NXN3_GASAC | ENSGACP00000000107 | ENSGACP00000010103 | Replication protein A3. | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). | 0.993 |
| G3N487_GASAC | G3P4E5_GASAC | ENSGACP00000000107 | ENSGACP00000012468 | Replication protein A3. | Uncharacterized protein. | 0.981 |
| G3N487_GASAC | G3P9V2_GASAC | ENSGACP00000000107 | ENSGACP00000014376 | Replication protein A3. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.993 |
| G3N487_GASAC | G3P9V9_GASAC | ENSGACP00000000107 | ENSGACP00000014383 | Replication protein A3. | BLM RecQ like helicase. | 0.993 |
| G3N487_GASAC | G3PIY1_GASAC | ENSGACP00000000107 | ENSGACP00000017560 | Replication protein A3. | RecQ helicase-like 5. | 0.932 |
| G3N487_GASAC | G3PLP7_GASAC | ENSGACP00000000107 | ENSGACP00000018528 | Replication protein A3. | RecQ mediated genome instability 2. | 0.861 |
| G3N487_GASAC | G3PQC5_GASAC | ENSGACP00000000107 | ENSGACP00000019810 | Replication protein A3. | RecQ helicase-like 4. | 0.972 |
| G3N487_GASAC | G3PR97_GASAC | ENSGACP00000000107 | ENSGACP00000020132 | Replication protein A3. | Tudor domain containing 3. | 0.972 |
| G3NI54_GASAC | G3N487_GASAC | ENSGACP00000005014 | ENSGACP00000000107 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A3. | 0.972 |
| G3NI54_GASAC | G3NKI9_GASAC | ENSGACP00000005014 | ENSGACP00000005852 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Excision repair cross-complementation group 4. | 0.970 |
| G3NI54_GASAC | G3NXN3_GASAC | ENSGACP00000005014 | ENSGACP00000010103 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). | 0.988 |
| G3NI54_GASAC | G3P4E5_GASAC | ENSGACP00000005014 | ENSGACP00000012468 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.999 |
| G3NI54_GASAC | G3P9V2_GASAC | ENSGACP00000005014 | ENSGACP00000014376 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.951 |
| G3NI54_GASAC | G3P9V9_GASAC | ENSGACP00000005014 | ENSGACP00000014383 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | BLM RecQ like helicase. | 0.983 |
| G3NI54_GASAC | G3PIY1_GASAC | ENSGACP00000005014 | ENSGACP00000017560 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RecQ helicase-like 5. | 0.960 |
| G3NI54_GASAC | G3PLP7_GASAC | ENSGACP00000005014 | ENSGACP00000018528 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RecQ mediated genome instability 2. | 0.961 |
| G3NI54_GASAC | G3PQC5_GASAC | ENSGACP00000005014 | ENSGACP00000019810 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | RecQ helicase-like 4. | 0.979 |
| G3NI54_GASAC | G3PR97_GASAC | ENSGACP00000005014 | ENSGACP00000020132 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Tudor domain containing 3. | 0.996 |
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