Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NIA4_GASACG protein-coupled receptor 143. (415 aa)    
Predicted Functional Partners:
G3PS16_GASAC
Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.952
ASS1
Argininosuccinate synthase 1.
  
 
 0.948
G3PPX0_GASAC
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family.
  
 0.935
G3NG75_GASAC
Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
   
 0.922
TYR
Tyrosinase.
   
 
 0.918
G3PM80_GASAC
Cytochrome b5 reductase 4.
  
 0.910
G3QB01_GASAC
Argininosuccinate lyase.
  
 
 0.910
G3NXX9_GASAC
Uridine monophosphate synthetase.
  
 
 0.892
G3ND17_GASAC
NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
  
 
 0.887
G3NVD2_GASAC
Oxidoreductase NAD-binding domain containing 1.
  
 
 0.887
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (18%) [HD]