STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NIL2_GASACUbiquitin protein ligase E3C. (973 aa)    
Predicted Functional Partners:
G3QA52_GASAC
Ubiquitin B.
   
 0.908
G3NX84_GASAC
Thyroid hormone receptor interactor 12.
   
 
 0.878
G3P3F7_GASAC
Ubiquitin protein ligase E3B.
   
 
0.872
G3PQX6_GASAC
Proteasome 26S subunit, non-ATPase 14.
    
 
 0.865
G3N5F0_GASAC
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.811
G3PH76_GASAC
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.791
G3NY48_GASAC
Zinc finger, AN1-type domain 4.
   
 0.777
G3P2M0_GASAC
Uncharacterized protein.
   
 0.772
UBL4A
Ubiquitin like 4A.
   
 0.772
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.749
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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