Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NIR5_GASACEGF-like-domain, multiple 6. (531 aa)    
Predicted Functional Partners:
G3P322_GASAC
WD repeat domain 90.
   
 0.763
G3NBC9_GASAC
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 
 0.746
G3P2T5_GASAC
WD repeat domain 24.
     
 0.736
G3PR09_GASAC
Patatin-like phospholipase domain containing 4.
      
 0.727
G3P2Q7_GASAC
Ankyrin repeat and sterile alpha motif domain containing 3.
   
 0.721
ARHGAP6-2
Rho GTPase activating protein 6.
    
 
 0.682
G3P2U5_GASAC
Rhomboid-related protein 1; May be involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors; Belongs to the peptidase S54 family.
    
 
 0.636
G3QAC6_GASAC
Uncharacterized protein.
    
 0.632
G3P303_GASAC
Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family.
    
 0.624
G3NQD6_GASAC
Neuron-derived neurotrophic factor.
      
 0.612
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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