Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1019 aa)    
Predicted Functional Partners:
G3NH35_GASAC
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.993
G3Q3E0_GASAC
Unc-93 homolog B1, TLR signaling regulator.
    
 0.951
G3P751_GASAC
Toll-like receptor 9; Belongs to the Toll-like receptor family.
     
0.908
G3NIU9_GASAC
Toll-like receptor 7; Belongs to the Toll-like receptor family.
  
  
 
0.904
G3PYF8_GASAC
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.897
G3NKU8_GASAC
Eukaryotic translation initiation factor 4h.
    
   0.811
G3PHV2_GASAC
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.746
G3NX60_GASAC
Transmembrane p24 trafficking protein 7.
   
 0.724
G3PVV3_GASAC
Transmembrane p24 trafficking protein 3.
   
 0.724
G3N5B5_GASAC
Inhibitor of nuclear factor kappa B kinase subunit epsilon.
   
 0.716
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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