Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NIS9_GASACUncharacterized protein. (368 aa)    
Predicted Functional Partners:
G3PXA6_GASAC
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
    
 0.928
G3P091_GASAC
Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family.
     
 0.872
G3NQY9_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 1.
     
 0.855
G3N5W4_GASAC
SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...]
     
 0.796
G3N871_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 2.
     
 0.774
G3NH56_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino.
     
  0.737
G3NCH0_GASAC
Biogenesis of lysosomal organelles complex-1, subunit 5, muted.
     
 0.703
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3.
   
 
 0.703
G3PGF7_GASAC
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.
     
 0.634
G3PBS9_GASAC
Dystrobrevin, beta b.
    
 
 0.590
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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