Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NJ16_GASACInterleukin-1 receptor-associated kinase 4. (485 aa)    
Predicted Functional Partners:
G3NH35_GASAC
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.999
G3PYF8_GASAC
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.999
G3N843_GASAC
Uncharacterized protein.
    
 0.997
G3NTJ8_GASAC
TIR domain-containing protein.
    
 0.996
G3NTV9_GASAC
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.981
G3N846_GASAC
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.973
G3PIJ0_GASAC
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.952
G3N6T6_GASAC
Pellino E3 ubiquitin protein ligase family member 3.
    
 0.950
G3PGX7_GASAC
Uncharacterized protein.
    
 0.950
PELI1
Pellino E3 ubiquitin protein ligase 1.
    
 0.950
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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