STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
G3NJ88_GASACDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)    
Predicted Functional Partners:
G3PG11_GASAC
X-ray repair complementing defective repair in Chinese hamster cells 1.
   
 0.988
G3NR62_GASAC
Polynucleotide kinase 3'-phosphatase.
    
 0.957
G3PBI6_GASAC
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
   
 0.957
G3QCE5_GASAC
DNA ligase.
  
 0.951
G3Q0X1_GASAC
Poly [ADP-ribose] polymerase.
   
 0.924
G3Q0G8_GASAC
DNA ligase.
  
 0.923
G3Q7A9_GASAC
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
   
 0.920
G3NLE6_GASAC
Nei-like DNA glycosylase 1.
   
 0.896
G3PPN5_GASAC
Tyrosyl-DNA phosphodiesterase 1.
   
 
 0.887
G3PM28_GASAC
DNA ligase.
  
 0.870
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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