| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENKD1 | FEN1 | ENSGACP00000005405 | ENSGACP00000002941 | Enkurin domain containing 1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.767 |
| ENKD1 | G3NM92_GASAC | ENSGACP00000005405 | ENSGACP00000006455 | Enkurin domain containing 1. | X-ray repair complementing defective repair in Chinese hamster cells 6. | 0.778 |
| ENKD1 | G3NQJ7_GASAC | ENSGACP00000005405 | ENSGACP00000007613 | Enkurin domain containing 1. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.755 |
| ENKD1 | G3NR62_GASAC | ENSGACP00000005405 | ENSGACP00000007829 | Enkurin domain containing 1. | Polynucleotide kinase 3'-phosphatase. | 0.848 |
| ENKD1 | G3PG11_GASAC | ENSGACP00000005405 | ENSGACP00000016535 | Enkurin domain containing 1. | X-ray repair complementing defective repair in Chinese hamster cells 1. | 0.918 |
| ENKD1 | G3PHK7_GASAC | ENSGACP00000005405 | ENSGACP00000017083 | Enkurin domain containing 1. | DNA polymerase. | 0.774 |
| ENKD1 | G3PM28_GASAC | ENSGACP00000005405 | ENSGACP00000018659 | Enkurin domain containing 1. | DNA ligase. | 0.798 |
| ENKD1 | G3PT40_GASAC | ENSGACP00000005405 | ENSGACP00000020776 | Enkurin domain containing 1. | Zgc:110269. | 0.767 |
| ENKD1 | G3Q0G8_GASAC | ENSGACP00000005405 | ENSGACP00000023360 | Enkurin domain containing 1. | DNA ligase. | 0.854 |
| ENKD1 | G3QCE5_GASAC | ENSGACP00000005405 | ENSGACP00000027561 | Enkurin domain containing 1. | DNA ligase. | 0.773 |
| FEN1 | ENKD1 | ENSGACP00000002941 | ENSGACP00000005405 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Enkurin domain containing 1. | 0.767 |
| FEN1 | G3NM92_GASAC | ENSGACP00000002941 | ENSGACP00000006455 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair complementing defective repair in Chinese hamster cells 6. | 0.780 |
| FEN1 | G3NQJ7_GASAC | ENSGACP00000002941 | ENSGACP00000007613 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.995 |
| FEN1 | G3NR62_GASAC | ENSGACP00000002941 | ENSGACP00000007829 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Polynucleotide kinase 3'-phosphatase. | 0.410 |
| FEN1 | G3PG11_GASAC | ENSGACP00000002941 | ENSGACP00000016535 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | X-ray repair complementing defective repair in Chinese hamster cells 1. | 0.823 |
| FEN1 | G3PHK7_GASAC | ENSGACP00000002941 | ENSGACP00000017083 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.989 |
| FEN1 | G3PM28_GASAC | ENSGACP00000002941 | ENSGACP00000018659 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.886 |
| FEN1 | G3PT40_GASAC | ENSGACP00000002941 | ENSGACP00000020776 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | Zgc:110269. | 0.850 |
| FEN1 | G3Q0G8_GASAC | ENSGACP00000002941 | ENSGACP00000023360 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.986 |
| FEN1 | G3QCE5_GASAC | ENSGACP00000002941 | ENSGACP00000027561 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA ligase. | 0.913 |