Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G3NJE0_GASACPlasminogen activator; Belongs to the peptidase S1 family. (578 aa)    
Predicted Functional Partners:
G3N6K3_GASAC
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family.
  
 0.998
G3N4R9_GASAC
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; Belongs to the serpin family.
  
 0.913
G3NR28_GASAC
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
    
 0.844
G3P9W0_GASAC
SERPIN domain-containing protein; Belongs to the serpin family.
   
 0.817
G3PW69_GASAC
Platelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.733
G3Q4A9_GASAC
Fibrinogen alpha chain.
   
 0.732
G3NGJ4_GASAC
Protein S100; Belongs to the S-100 family.
   
 0.724
G3PPF4_GASAC
Uncharacterized protein.
   
 0.676
G3N4U6_GASAC
Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3; Belongs to the serpin family.
   
 0.664
G3NZ98_GASAC
Matrix metallopeptidase 9.
     
 0.656
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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