| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| G3NFY2_GASAC | G3NJG9_GASAC | ENSGACP00000004237 | ENSGACP00000005480 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | Potassium channel tetramerization domain containing 2. | 0.971 |
| G3NFY2_GASAC | G3NLZ6_GASAC | ENSGACP00000004237 | ENSGACP00000006359 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | Ran GTPase activating protein 1b. | 0.479 |
| G3NFY2_GASAC | G3NQJ7_GASAC | ENSGACP00000004237 | ENSGACP00000007613 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.549 |
| G3NFY2_GASAC | G3NS82_GASAC | ENSGACP00000004237 | ENSGACP00000008199 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.593 |
| G3NFY2_GASAC | G3NXS0_GASAC | ENSGACP00000004237 | ENSGACP00000010140 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | RAN GTPase activating protein 1a. | 0.532 |
| G3NFY2_GASAC | G3PFG4_GASAC | ENSGACP00000004237 | ENSGACP00000016338 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | SUMO1 activating enzyme subunit 1. | 0.999 |
| G3NFY2_GASAC | G3PHQ9_GASAC | ENSGACP00000004237 | ENSGACP00000017135 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | RAN binding protein 1. | 0.463 |
| G3NFY2_GASAC | G3PSG8_GASAC | ENSGACP00000004237 | ENSGACP00000020554 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | Small ubiquitin-related modifier. | 0.998 |
| G3NFY2_GASAC | RANBP2 | ENSGACP00000004237 | ENSGACP00000009078 | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | RAN binding protein 2. | 0.742 |
| G3NJG9_GASAC | G3NFY2_GASAC | ENSGACP00000005480 | ENSGACP00000004237 | Potassium channel tetramerization domain containing 2. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.971 |
| G3NJG9_GASAC | G3NLZ6_GASAC | ENSGACP00000005480 | ENSGACP00000006359 | Potassium channel tetramerization domain containing 2. | Ran GTPase activating protein 1b. | 0.947 |
| G3NJG9_GASAC | G3NQJ7_GASAC | ENSGACP00000005480 | ENSGACP00000007613 | Potassium channel tetramerization domain containing 2. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.954 |
| G3NJG9_GASAC | G3NS82_GASAC | ENSGACP00000005480 | ENSGACP00000008199 | Potassium channel tetramerization domain containing 2. | NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. | 0.931 |
| G3NJG9_GASAC | G3NXS0_GASAC | ENSGACP00000005480 | ENSGACP00000010140 | Potassium channel tetramerization domain containing 2. | RAN GTPase activating protein 1a. | 0.947 |
| G3NJG9_GASAC | G3PEE9_GASAC | ENSGACP00000005480 | ENSGACP00000015973 | Potassium channel tetramerization domain containing 2. | RAD52 homolog, DNA repair protein. | 0.916 |
| G3NJG9_GASAC | G3PFG4_GASAC | ENSGACP00000005480 | ENSGACP00000016338 | Potassium channel tetramerization domain containing 2. | SUMO1 activating enzyme subunit 1. | 0.967 |
| G3NJG9_GASAC | G3PHQ9_GASAC | ENSGACP00000005480 | ENSGACP00000017135 | Potassium channel tetramerization domain containing 2. | RAN binding protein 1. | 0.931 |
| G3NJG9_GASAC | G3PSG8_GASAC | ENSGACP00000005480 | ENSGACP00000020554 | Potassium channel tetramerization domain containing 2. | Small ubiquitin-related modifier. | 0.977 |
| G3NJG9_GASAC | RANBP2 | ENSGACP00000005480 | ENSGACP00000009078 | Potassium channel tetramerization domain containing 2. | RAN binding protein 2. | 0.997 |
| G3NLZ6_GASAC | G3NFY2_GASAC | ENSGACP00000006359 | ENSGACP00000004237 | Ran GTPase activating protein 1b. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.479 |