STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
G3NJK0_GASACDual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B. (634 aa)    
Predicted Functional Partners:
G3NVV0_GASAC
Ddb1 and cul4 associated factor 7.
   
 
 0.892
DCAF7
DDB1 and CUL4 associated factor 7.
   
 
 0.892
G3NQX8_GASAC
Lin-52 DREAM MuvB core complex component.
    
 0.814
G3Q6V4_GASAC
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.780
G3NBF4_GASAC
CRC domain-containing protein.
   
 0.701
G3PSX7_GASAC
Lin-54 DREAM MuvB core complex component.
   
 0.701
G3NXM5_GASAC
Lin-37 DREAM MuvB core complex component.
    
 0.695
G3NL94_GASAC
Uncharacterized protein.
    
 
 0.683
G3PBM1_GASAC
Lin-9 DREAM MuvB core complex component.
    
 0.682
G3NM42_GASAC
E1A binding protein p300 a.
   
 0.679
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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