GNG4 protein (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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co-expression

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gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVPR1A	GNG4	ENSGACP00000004706	ENSGACP00000005598	Arginine vasopressin receptor 1Aa.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.948
AVPR1A	POMC	ENSGACP00000004706	ENSGACP00000012552	Arginine vasopressin receptor 1Aa.	Proopiomelanocortin a.	0.508
G3NSK8_GASAC	GNG4	ENSGACP00000008326	ENSGACP00000005598	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.980
G3Q6U4_GASAC	GNG4	ENSGACP00000025604	ENSGACP00000005598	Phosphoinositide-3-kinase, regulatory subunit 5.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.967
GHRHR	GNG4	ENSGACP00000015575	ENSGACP00000005598	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.941
GHSR	GNG4	ENSGACP00000014489	ENSGACP00000005598	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.960
GHSR	POMC	ENSGACP00000014489	ENSGACP00000012552	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	Proopiomelanocortin a.	0.778
GNG4	AVPR1A	ENSGACP00000005598	ENSGACP00000004706	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Arginine vasopressin receptor 1Aa.	0.948
GNG4	G3NSK8_GASAC	ENSGACP00000005598	ENSGACP00000008326	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.980
GNG4	G3Q6U4_GASAC	ENSGACP00000005598	ENSGACP00000025604	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Phosphoinositide-3-kinase, regulatory subunit 5.	0.967
GNG4	GHRHR	ENSGACP00000005598	ENSGACP00000015575	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.941
GNG4	GHSR	ENSGACP00000005598	ENSGACP00000014489	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Growth hormone secretagogue receptor b; Belongs to the G-protein coupled receptor 1 family.	0.960
GNG4	HCRTR2	ENSGACP00000005598	ENSGACP00000008354	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Hypocretin (orexin) receptor 2.	0.966
GNG4	LHCGR	ENSGACP00000005598	ENSGACP00000007358	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.946
GNG4	OPRDb	ENSGACP00000005598	ENSGACP00000009687	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Opioid receptor, delta 1b; Belongs to the G-protein coupled receptor 1 family.	0.935
GNG4	POMC	ENSGACP00000005598	ENSGACP00000012552	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Proopiomelanocortin a.	0.959
GNG4	TSHR	ENSGACP00000005598	ENSGACP00000003575	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	0.946
HCRTR2	GNG4	ENSGACP00000008354	ENSGACP00000005598	Hypocretin (orexin) receptor 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.966
HCRTR2	POMC	ENSGACP00000008354	ENSGACP00000012552	Hypocretin (orexin) receptor 2.	Proopiomelanocortin a.	0.608
LHCGR	GNG4	ENSGACP00000007358	ENSGACP00000005598	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.946