Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NK10_GASACUncharacterized protein. (763 aa)    
Predicted Functional Partners:
G3P9P8_GASAC
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.999
G3NLR4_GASAC
DNA topoisomerase II binding protein 1.
    
 0.997
G3NSY0_GASAC
Uncharacterized protein.
    
 0.993
G3QBM7_GASAC
Checkpoint kinase 1; Belongs to the protein kinase superfamily.
    
 0.986
G3P9V2_GASAC
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.981
RPA1
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.981
G3P835_GASAC
Uncharacterized protein.
    
 0.948
G3N424_GASAC
DNA helicase; Belongs to the MCM family.
    
 0.930
G3Q7X4_GASAC
Uncharacterized protein.
    
 
 0.925
G3QBX6_GASAC
RAD50 homolog, double strand break repair protein.
    
 0.923
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
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