Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
G3NK22_GASACTranslocase of outer mitochondrial membrane 20. (1271 aa)    
Predicted Functional Partners:
G3PMJ2_GASAC
SDS3 homolog, SIN3A corepressor complex component.
   
 0.977
G3P6G7_GASAC
Actin-like 6A; Belongs to the actin family.
   
 0.975
G3QCA7_GASAC
Sap30-like.
    
 0.974
RBBP4
RB binding protein 4, chromatin remodeling factor.
   
 0.965
RBBP4-2
RB binding protein 4, chromatin remodeling factor.
   
 0.965
G3PNN8_GASAC
Retinoblastoma binding protein 4, like.
   
 0.965
G3Q0Q6_GASAC
Uncharacterized protein.
   
 0.965
G3NHY7_GASAC
Sin3A-associated protein a.
    
 0.955
G3NN24_GASAC
BRMS1 like transcriptional repressor b.
   
 0.955
G3NW49_GASAC
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.955
Your Current Organism:
Gasterosteus aculeatus
NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.