TLR5 protein (Gasterosteus aculeatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Gasterosteus aculeatus

NCBI taxonomy Id: 69293
Other names: G. aculeatus, three spined stickleback, three-spined stickleback

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G3N843_GASAC	G3N846_GASAC	ENSGACP00000001477	ENSGACP00000001480	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.847
G3N843_GASAC	G3NH35_GASAC	ENSGACP00000001477	ENSGACP00000004643	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.998
G3N843_GASAC	G3NJ16_GASAC	ENSGACP00000001477	ENSGACP00000005326	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 4.	0.997
G3N843_GASAC	G3NTJ8_GASAC	ENSGACP00000001477	ENSGACP00000008666	Uncharacterized protein.	TIR domain-containing protein.	0.986
G3N843_GASAC	G3NVU5_GASAC	ENSGACP00000001477	ENSGACP00000009464	Uncharacterized protein.	Uncharacterized protein.	0.641
G3N843_GASAC	G3NX60_GASAC	ENSGACP00000001477	ENSGACP00000009929	Uncharacterized protein.	Transmembrane p24 trafficking protein 7.	0.620
G3N843_GASAC	G3PYF8_GASAC	ENSGACP00000001477	ENSGACP00000022648	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.998
G3N843_GASAC	G3Q1H0_GASAC	ENSGACP00000001477	ENSGACP00000023718	Uncharacterized protein.	Toll-like receptor 1; Belongs to the Toll-like receptor family.	0.602
G3N843_GASAC	TLR5	ENSGACP00000001477	ENSGACP00000005783	Uncharacterized protein.	Toll like receptor 5; Belongs to the Toll-like receptor family.	0.641
G3N846_GASAC	G3N843_GASAC	ENSGACP00000001480	ENSGACP00000001477	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.847
G3N846_GASAC	G3NH35_GASAC	ENSGACP00000001480	ENSGACP00000004643	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.984
G3N846_GASAC	G3NJ16_GASAC	ENSGACP00000001480	ENSGACP00000005326	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Interleukin-1 receptor-associated kinase 4.	0.973
G3N846_GASAC	G3NTJ8_GASAC	ENSGACP00000001480	ENSGACP00000008666	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TIR domain-containing protein.	0.874
G3N846_GASAC	G3NVU5_GASAC	ENSGACP00000001480	ENSGACP00000009464	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.641
G3N846_GASAC	G3NX60_GASAC	ENSGACP00000001480	ENSGACP00000009929	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Transmembrane p24 trafficking protein 7.	0.620
G3N846_GASAC	G3PYF8_GASAC	ENSGACP00000001480	ENSGACP00000022648	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.988
G3N846_GASAC	G3Q1H0_GASAC	ENSGACP00000001480	ENSGACP00000023718	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Toll-like receptor 1; Belongs to the Toll-like receptor family.	0.602
G3N846_GASAC	TLR5	ENSGACP00000001480	ENSGACP00000005783	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Toll like receptor 5; Belongs to the Toll-like receptor family.	0.641
G3NH35_GASAC	G3N843_GASAC	ENSGACP00000004643	ENSGACP00000001477	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.998
G3NH35_GASAC	G3N846_GASAC	ENSGACP00000004643	ENSGACP00000001480	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.984